Manufacturing

Every bottle, sterilized at 121°C.

Primary container

Engineered to be exceptional.

Medical-grade polypropylene primary container: Body, neck and hanger are formed as one piece on this site, so no empty bottle is ever shipped in, stored or washed.
Tamper-evident peel-off overseal: A peel-off seal you can see has never been opened, over a medical-grade rubber disk.
Dual-site spike disk: Two spike points, each one-way, so two giving sets can run at once without leaking.
Integral rotatable hanger: Moulded as part of the bottle, and turns so the bottle hangs straight on any stand.

Sterifluid I.V. bottle in exploded view: peel-off overseal, outer cap, medical-grade rubber disk, inner cap, polypropylene body and rotatable hanger, with the 121°C terminal sterilization callout — Sterifluid primary container. Group technical literature.

Every product, made under one roof.

Products from 5 ml to 1,000 ml, every registration manufactured on this site.

STERIFLUID · 100–1,000 ml

Large-volume crystalloids

The replacement fluids used in hospitals every day: dextrose, saline, dextrose-saline, Ringer and Ringer lactate.

Sterifluid 5 / 10 / 25%Dextrose
Sterifluid NSSodium chloride 0.9%
Sterifluid DSDextrose 5% + sodium chloride 0.9%
Sterifluid R / RL / RLDRinger and Ringer lactate
Sterifluid N/3One-third saline
Sterifluid PaedsPaediatric maintenance

MINI

Small-volume parenterals

Water for injection and concentrated electrolytes, filled in the same polypropylene system as the large-volume line.

Mini WFISterile water for injection
Mini NaClSodium chloride 0.9%
Mini BCSodium bicarbonate 8.4%
Potassium chloride 7.45%Small-volume parenteral

STERI · 100–250 ml

Ready-to-use anti-infectives

I.V. antibiotics supplied premixed, so they are not reconstituted on the ward.

SterimetMetronidazole 500 mg / 100 ml
SteriofloxOfloxacin 200 mg / 100 ml
SterilevoLevofloxacin 500 mg / 100 ml
StericiproCiprofloxacin 200 mg / 100 ml
SterimoxMoxifloxacin 400 mg / 250 ml

STERILYTE · STERIFLUTOL · 500–1,000 ml

Maintenance and osmotic solutions

Electrolyte-dextrose maintenance, and a mannitol–sorbitol osmotic infusion. Same plant, same terminal sterilization.

Sterilyte-MElectrolytes + dextrose
Steriflutol-20Mannitol 17.5% + sorbitol 2.5%

The cycle

A world-class sterilization cycle.

The sealed bottle is heated to 121°C. That kills bacteria in the finished unit. Bacterial toxins are kept out of the water, and every batch is tested for them before release.

Method: Terminal moist heat, in the sealed final container
Reference: 121°C (250°F) · Ph. Eur. 5.1.1
Lethality: F₀ ≥ 8 min at 121°C, z = 10°C
Assurance: Sterility assurance level 10⁻⁶ or better
Validated at: The point of the load that heats last

Bacterial toxins (endotoxins) are controlled where they can arise: Water for Injection, tight limits on incoming materials, short holds before the autoclave. Every batch is tested before release.

Quality comes first.

Raw-material analysis

Incoming materials are checked before they enter the line.

In-process checks

Intermediates are held to written specifications at each stage.

Finished-product analysis

Released units are tested. Traceability is recorded against the SOP.

Stability studies

A standing programme, held to written protocols.

Inside one of Pakistan’s largest I.V. plants.

Mixing vessels with their agitator drives — The mixing hall, where the solution is made.

Polypropylene bottles leaving the blow-moulding machine — Bottle blowing. New polypropylene bottles leave the machine on site.

Gowned operator at the filling line — Filling line. The operator is gowned and masked.

Filled polypropylene I.V. bottles on the outfeed conveyor — Filled units leaving the filler.